UTEP Postdoctoral Career Transition Program in Cancer Research - CPRIT (08/01/2023-08/31/2023)
STARs Award - The University of Texas System (09/01/2022)
The Basic Science Research Award - Department of Medicine at Stony Brook University (01/01/2021-12/31/2021)
Idea Award, Peer-Reviewed Cancer Research Program - Department of Defense (01/01/2020-12/31/2020)
NIDDK R01 Award - NIH (01/01/2020-12/31/2020)
R01 - NCI (01/01/2020-12/31/2020)
Research Scholar Award - American Cancer Society (01/01/2020-12/31/2020)
Pilot Project Grant - Department of Medicine, Stony Brook University (01/01/2020)
NIH High Priority R56 Award - NIH (09/01/2019-09/30/2019)
Finalist in Faculty Category-13th Annual Women in Medicine Research Day - Stony Brook University School of Medicine (03/01/2019-03/31/2019)
SUNY Central Award - Stony Brook University (01/01/2019-01/31/2019)
Finalist in Faculty Category-11th Annual Women in Medicine Research Day - Stony Brook University School of Medicine (03/01/2017-03/31/2017)
Pilot Project Grant - Department of Medicine, Stony Brook University (01/01/2017)
Young Investigator Award - American Pancreatic Association (11/15/2015)
Khalifa Bin Zayed Al Nahyan Research Award - MD Anderson Cancer Center (09/01/2014)
Khalifa Bin Zayed Al Nahyan Research Award - MD Anderson Cancer Center (09/01/2014)
Predoctoral Fellowship Award - University of Texas-Graduate School of Biomedical Sciences, Houston, TX (08/20/2003)
Education
Ph D in Molecular Pathology, University of Texas Health Science Center (2008)
Publications
Early elevations of RAS protein level and activity are critical for the development of PDAC in the context of inflammation. Cancer letters (2024),
J Ma, F Gong, Eunja Kim, J X. Du , C Leung, S Qingchun, C D. Logsdon, Y Luo, X Li , Weiqin Lu.
Targeting the FGF19-FGFR4 pathway for cholestatic, metabolic, and cancerous diseases. Journal of internal medicine (2024),
X Li , Weiqin Lu, A Kharitonenkov, Y Luo.
Oncogenic KRASG12D Reprograms Lipid Metabolism by Upregulating SLC25A1 to Drive Pancreatic Tumorigenesis. Cancer Research Cancer Research 83 22 (2023),
R Zhang, X Peng, J X. Du , R Boohaker, I L. Estevao, B I. Grajeda, Marc B. Cox, Igor C. Almeida, Weiqin Lu.
Methionine restriction sensitizes cancer cells to immunotherapy. Cancer communications (London, England) 43 11 (2023),
Weiqin Lu, Y Luo.
Oncogenic KRASG12D reprograms lipid metabolism by upregulating SLC25A1 to drive pancreatic tumorigenesis Cancer Research 83 22 (2023),
R. Zhang, X. Peng, J.X. Du, R. Boohaker, I. Estevao, B. Grajeda, Marc B. Cox, Igor C. Almeida, Weiqin Lu.
Differential Effects of Dietary Macronutrients on the Development of Oncogenic KRAS-Mediated Pancreatic Ductal Adenocarcinoma CANCERS 14 11 (2022),
Liang Zhu, Juntao Ji, Jianjia Ma, Dan Wang, Muyun Liu, James X. Du, Rong Chen, Wei Hou, James L. Abbruzzese, Craig D. Logsdon, Vincent W. Yang, Yongde Luo, Weiqin Lu.
FGF21 in obesity and cancer: New insights CANCER LETTERS 499 (2021),
Weiqin Lu, Xiaokun Li, Yongde Luo.
Pancreatic Tumorigenesis: Oncogenic KRAS and the Vulnerability of the Pancreas to Obesity CANCERS 13 4 (2021),
Yongde Luo, Xiaokun Li, Jianjia Ma, James L. Abbruzzese, Weiqin Lu.
Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis CELL DEATH & DISEASE 12 2 (2021),
Muyun Liu, Dan Wang, Yongde Luo, Lianghao Hu, Yawei Bi, Juntao Ji, Haojie Huang, Guoqiang Wang, Liang Zhu, Jianjia Ma, Eunice Kim, Catherine K. Luo, James L. Abbruzzese, Xiaokun Li, Vincent W. Yang, Zhaoshen Li, Weiqin Lu.
The Significance of Mitochondrial Dysfunction in Cancer INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 16 (2020),
Yongde Luo, Jianjia Ma, Weiqin Lu.
Emerging Structure-Function Paradigm of Endocrine FGFs in Metabolic Diseases TRENDS IN PHARMACOLOGICAL SCIENCES 40 2 (2019),
Yongde Luo, Sheng Ye, Xiaokun Li, Weiqin Lu.
Measurement of Reactive Oxygen Species by Fluorescent Probes in Pancreatic Cancer Cells PANCREATIC CANCER, 3 EDITION 1882 (2019),
Yongde Luo, Dan Wang, James L. Abbruzzese, Weiqin Lu.
Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS CELL COMMUNICATION AND SIGNALING 17 (2019),
Dan Wang, Yawei Bi, Lianghao Hu, Yongde Luo, Juntao Ji, Albert Z. Mao, Craig D. Logsdon, Ellen Li, James L. Abbruzzese, Zhaoshen Li, Vincent W. Yang, Weiqin Lu.
Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet GASTROENTEROLOGY 157 5 (2019),
Yongde Luo, Yaying Yang, Muyun Liu, Dan Wang, Feng Wang, Yawei Bi, Juntao Ji, Suyun Li, Yan Liu, Rong Chen, Haojie Huang, Xiaojie Wang, Agnieszka K. Swidnicka-Siergiejko, Tobias Janowitz, Semir Beyaz, Guoqiang Wang, Sulan Xu, Agnieszka B. Bialkowska, Catherine K. Luo, Christoph L. Pin, Guang Liang, Xiongbin Lu, Maoxin Wu, Kenneth R. Shroyer, Robert A. Wolff, William Plunkett, Baoan Ji, Zhaoshen Li, Ellen Li, Xiaokun Li, Vincent W. Yang, Craig D. Logsdon, James L. Abbruzzese, Weiqin Lu.
Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 316 1 (2019),
Haojie Huang, Jiaxiang Chen, Lisi Peng, Yao Yao, Defeng Deng, Yang Zhang, Yan Liu, Huamin Wang, Zhaoshen Li, Yan Bi, Ashley N. Haddock, Xianbao Zhan, Weiqin Lu, Craig D. Logsdon, Baoan Ji.
Presentations
Obesity and Pancreatic Cancer (2023),
Weiqin Lu.
Revisit Oncogenic KRAS in Pancreatic Cancer Development (2023),
Weiqin Lu.
Obesity, ROS, and Pancreatic Cancer (2023), Volume online,
Weiqin Lu.
Oncogenic KrasG12D reprograms lipid metabolism by regulating SLC25A1 expression to drive pancreatic tumorigenesis. (2022), Volume FL,
Weiqin Lu.
RAS activation in oncogenic KRAS and IKK2 mediated pancreatic ductal adenocarcinoma (2022), Volume Stony Brook, NY,
Weiqin Lu.
Oncogenic KrasG12D reprograms lipid metabolism by regulating SLC25A1 expression to drive pancreatic tumorigenesis (2022), Volume Stony Brook, NY,
Weiqin Lu.
Pancreatic Cancer and Its Risk Factors (2022),
Weiqin Lu.
Obesity and Pancreatic Cancer (2022),
Weiqin Lu.
High-Fat Diet and Pancreatic Cancer (2021), Volume Stony Brook University,
Weiqin Lu.
Obesity, Inflammation, and Pancreatic Cancer (2021),
Weiqin Lu.
Unraveling the Mechanistic Link between Obesity and Pancreatic Cancer (2021),
Weiqin Lu.
Mechanistic Link Between Obesity and Pancreatic Cancer (2021), Volume Stony Brook University,
Weiqin Lu.
Targeting Redox Metabolism for Pancreatic Cancer Therapy (2021), Volume Stony Brook University,
Weiqin Lu.
Unraveling the Mechanistic Link between Obesity and Pancreatic Cancer (2021), Volume Tulane University School of Medicine. ,
Weiqin Lu.
Pancreatic Tumorigenesis: Oncogenic KRAS and the Vulnerability of the Pancreas to Obesity (2021), Volume The University of Toledo,
Weiqin Lu.
Unraveling the Mechanistic Link Between Obesity and PDAC. (2021), Volume Tianjing, China,
Weiqin Lu.
High-Fat Diet and Pancreatic Cancer (2020), Volume Stony Brook University Cancer Center,
Weiqin Lu.
Unraveling the Mechanistic Link Between High-Fat Diet and Pancreatic Cancer (2020), Volume Department of Medicine, Stony Brook University,
Weiqin Lu.
Interplay between Inflammation and Oncogenic KRAS in Pancreatic Tumorigenesis (2020), Volume Stony Brook University,
Weiqin Lu.
Impact of High-Fat Diet on Pancreatic Tumorigenesis (2020), Volume Stony Brook University Cancer Center.,
Weiqin Lu.
The Role of High‐Fat Diet in Pancreatic Cancer Development (2020), Volume The Department of Pharmacological Sciences, Stony Brook University School of Medicine, NY.,
Weiqin Lu.
Role of Obesity and Inflammation in Pancreatic Cancer Development (2020), Volume Stony Brook University School of Medicine, NY.,
Weiqin Lu.
Obesogenic High-Fat Diet and Oncogenic KRAS in Pancreatic Tumorigenesis. (2020), Volume Stony Brook University School of Medicine, NY. ,
Weiqin Lu.
Oncogenic KRAS Reduces Expression of FGF21 to Promote Pancreatic Tumorigenesis. (2019), Volume Jiangxi, China,
Weiqin Lu.
Role of NADPH Oxidase in Pancreatic Tumorigenesis (2019), Volume Department of Medicine , Stony Brook University School of Medicine, NY. ,
Weiqin Lu.
Grants
CPRIT: TREC: Institutional Postdoctoral Training Award
UTEP Postdoctoral Career Transition Program in Cancer Research - CPRIT (08/01/2023-08/31/2023)
STARs Award - The University of Texas System (09/01/2022)
The Basic Science Research Award - Department of Medicine at Stony Brook University (01/01/2021-12/31/2021)
Idea Award, Peer-Reviewed Cancer Research Program - Department of Defense (01/01/2020-12/31/2020)
NIDDK R01 Award - NIH (01/01/2020-12/31/2020)
R01 - NCI (01/01/2020-12/31/2020)
Research Scholar Award - American Cancer Society (01/01/2020-12/31/2020)
Pilot Project Grant - Department of Medicine, Stony Brook University (01/01/2020)
NIH High Priority R56 Award - NIH (09/01/2019-09/30/2019)
Finalist in Faculty Category-13th Annual Women in Medicine Research Day - Stony Brook University School of Medicine (03/01/2019-03/31/2019)
SUNY Central Award - Stony Brook University (01/01/2019-01/31/2019)
Finalist in Faculty Category-11th Annual Women in Medicine Research Day - Stony Brook University School of Medicine (03/01/2017-03/31/2017)
Pilot Project Grant - Department of Medicine, Stony Brook University (01/01/2017)
Young Investigator Award - American Pancreatic Association (11/15/2015)
Khalifa Bin Zayed Al Nahyan Research Award - MD Anderson Cancer Center (09/01/2014)
Khalifa Bin Zayed Al Nahyan Research Award - MD Anderson Cancer Center (09/01/2014)
Predoctoral Fellowship Award - University of Texas-Graduate School of Biomedical Sciences, Houston, TX (08/20/2003)
Ph D in Molecular Pathology, University of Texas Health Science Center (2008)
Publications
Early elevations of RAS protein level and activity are critical for the development of PDAC in the context of inflammation. Cancer letters (2024),
J Ma, F Gong, Eunja Kim, J X. Du , C Leung, S Qingchun, C D. Logsdon, Y Luo, X Li , Weiqin Lu.
Targeting the FGF19-FGFR4 pathway for cholestatic, metabolic, and cancerous diseases. Journal of internal medicine (2024),
X Li , Weiqin Lu, A Kharitonenkov, Y Luo.
Oncogenic KRASG12D Reprograms Lipid Metabolism by Upregulating SLC25A1 to Drive Pancreatic Tumorigenesis. Cancer Research Cancer Research 83 22 (2023),
R Zhang, X Peng, J X. Du , R Boohaker, I L. Estevao, B I. Grajeda, Marc B. Cox, Igor C. Almeida, Weiqin Lu.
Methionine restriction sensitizes cancer cells to immunotherapy. Cancer communications (London, England) 43 11 (2023),
Weiqin Lu, Y Luo.
Oncogenic KRASG12D reprograms lipid metabolism by upregulating SLC25A1 to drive pancreatic tumorigenesis Cancer Research 83 22 (2023),
R. Zhang, X. Peng, J.X. Du, R. Boohaker, I. Estevao, B. Grajeda, Marc B. Cox, Igor C. Almeida, Weiqin Lu.
Presentations
Obesity and Pancreatic Cancer (2023),
Weiqin Lu.
Revisit Oncogenic KRAS in Pancreatic Cancer Development (2023),
Weiqin Lu.
Obesity, ROS, and Pancreatic Cancer (2023), Volume online,
Weiqin Lu.
Oncogenic KrasG12D reprograms lipid metabolism by regulating SLC25A1 expression to drive pancreatic tumorigenesis. (2022), Volume FL,
Weiqin Lu.
RAS activation in oncogenic KRAS and IKK2 mediated pancreatic ductal adenocarcinoma (2022), Volume Stony Brook, NY,
Weiqin Lu.
CPRIT: TREC: Institutional Postdoctoral Training Award