Young Investigator Contest best award - The Veterans Research Foundation of Pittsburgh (01/01/2020-12/31/2020)
Young Investigator Contest best award - The Veterans Research Foundation of Pittsburgh (01/01/2019-12/31/2019)
Best poster award - Korea-Japan Joint Symposium of Society of Pharmacology (01/01/2012-12/31/2012)
Korea Research Foundation (KRF/KOSEF) Fellowship for Ph.D. study - Korea Research Foundation (KRF/KOSEF) (01/01/2004-12/31/2004)
Full scholarship by The Royal Netherlands Government for M.Sc. study - The Royal Netherlands Government (01/01/2002-12/31/2002)
Education
Ph D in Biomolecular Science, University of Science and Technology (2010)
MS in Post-Harvest and Food Process Engineering, Asian Institute of Technology (2003)
BS in Biotechnology, Khulna University (2000)
Publications
Efficacy of novel SPAK inhibitor ZT-1a derivatives (1c, 1d, 1g & 1h) on improving post-stroke neurological outcome and brain lesion in mice NEUROCHEMISTRY INTERNATIONAL 162 (2023),
Mohammad Iqbal H. Bhuiyan, Sydney Fischer, Shivani M. Patel, Helena Oft, Ting Zhang, Lesley M. Foley, Jinwei Zhang, T. K. Hitchens, Bradley J. Molyneaux, Xianming Deng, Dandan Sun.
Near infrared spectroscopy detection of hemispheric cerebral ischemia following middle cerebral artery occlusion in rats NEUROCHEMISTRY INTERNATIONAL 162 (2023),
Ardy Wong, Mohammad Iqbal H. Bhuiyan, Jeffrey Rothman, Kelly Drew, Kambiz Pourrezaei, Dandan Sun, Zeinab Barati.
NF-kappa B Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice STROKE 53 5 (2022),
Mohammad Iqbal H. Bhuiyan, Cullen B. Young, Israt Jahan, Md Hasan, Sydney Fischer, Azlan, Nur Farah Meor, Mingjun Liu, Ansuman Chattopadhyay, Huachen Huang, Kristopher T. Kahle, Jinwei Zhang, Samuel M. Poloyac, Bradley J. Molyneaux, Adam C. Straub, Xianming Deng, Delphine Gomez, Dandan Sun.
Role of SPAK-NKCC1 signaling cascade in the choroid plexus blood-CSF barrier damage after stroke JOURNAL OF NEUROINFLAMMATION 19 1 (2022),
Jun Wang, Ruijia Liu, Md Hasan, Sydney Fischer, Yang Chen, Matt Como, Victoria M. Fiesler, Mohammad Iqbal H. Bhuiyan, Shuying Dong, Eric Li, Kristopher T. Kahle, Jinwei Zhang, Xianming Deng, Arohan R. Subramanya, Gulnaz Begum, Yan Yin, Dandan Sun.
Activation of endothelial Wnt/beta-catenin signaling by protective astrocytes repairs BBB damage in ischemic stroke PROGRESS IN NEUROBIOLOGY 199 (2021),
Shanshan Song, Huachen Huang, Xiudong Guan, Victoria Fiesler, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Shayan Jalali, Md Hasan, Albert K. Tai, Ansuman Chattopadhyay, Srilakshmi Chaparala, Ming Sun, Donna B. Stolz, Pingnian He, Dritan Agalliu, Dandan Sun, Gulnaz Begum.
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function JOURNAL OF NEUROINFLAMMATION 18 1 (2021),
Qian Liu, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Shanshan Song, Gulnaz Begum, Cullen B. Young, Lesley M. Foley, Fenghua Chen, T. K. Hitchens, Guodong Cao, Ansuman Chattopadhyay, Li He, Dandan Sun.
Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells THERANOSTICS 11 3 (2021),
Md Hasan, Lanxin Luo, Dawei Ding, Shanshan Song, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Lesley M. Foley, Xiudong Guan, Gary Kohanbash, T. K. Hitchens, Maria G. Castro, Zhongling Zhang, Dandan Sun.
Reducing Reactive Astrocytes Improves Cognitive Function in a Mouse Model of Vascular Cognitive Impairment and Dementia. STROKE 52 (2021),
Liu Qian, Mohammad Iqbal H. Bhuiyan, Song Shanshan, Gulnaz Begum, Liu Ruijia, Chen Fenghua, Cao Guodong, He Li, Sun Dandan.
SPAK/OSR1 Signaling as a Novel Target for Post-Stroke Oxidative Stress Brain Injury. STROKE 52 (2021),
Wang Jun, Victoria M. Fiesler, Gulnaz Begum, Mohammad Iqbal H. Bhuiyan, Dong Shuying, Eric Li, Kristopher T. Kahle, Zhang Jinwei, Deng Xianming, Yin Yan, Sun Dandan.
Modulation of brain cation-Cl- cotransport via the SPAK kinase inhibitor ZT-1a NATURE COMMUNICATIONS 11 1 (2020),
Jinwei Zhang, Mohammad Iqbal H. Bhuiyan, Ting Zhang, Jason K. Karimy, Zhijuan Wu, Victoria M. Fiesler, Jingfang Zhang, Huachen Huang, Md Hasan, Anna E. Skrzypiec, Mariusz Mucha, Daniel Duran, Wei Huang, Robert Pawlak, Lesley M. Foley, T. K. Hitchens, Margaret B. Minnigh, Samuel M. Poloyac, Seth L. Alper, Bradley J. Molyneaux, Andrew J. Trevelyan, Kristopher T. Kahle, Dandan Sun, Xianming Deng.
A Novel Na+-K+-Cl- Cotransporter 1 Inhibitor STS66*Reduces Brain Damage in Mice After Ischemic Stroke STROKE 50 4 (2019),
Huachen Huang, Mohammad Iqbal H. Bhuiyan, Tong Jiang, Shanshan Song, Sandhya Shankar, Taraneh Taheri, Eric Li, Philipp Schreppel, Michael Hintersteininger, Sung-Sen Yang, Shih-Hua Lin, Bradley J. Molyneaux, Zhongling Zhang, Thomas Erker, Dandan Sun.
Black Rice (Oryza sativa L., Poaceae) Extract Reduces Hippocampal Neuronal Cell Death Induced by Transient Global Cerebral Ischemia in Mice EXPERIMENTAL NEUROBIOLOGY 27 2 (2018),
Sun-Nyoung Hwang, Jae-Cheon Kim, Mohammad Iqbal H. Bhuiyan, Joo Y. Kim, Ji S. Yang, Shin H. Yoon, Kee D. Yoon, Seong Y. Kim.
Effects of novel NKCC1 inhibitors on reducing brain damage and neurological deficits after ischemic stroke in mice FASEB JOURNAL 32 1 (2018),
Huachen Huang, Mohammad Iqbal H. Bhuiyan, Tong Jiang, Sandhya Shankar, Philipp Schreppel, Thomas Erker, Michael Hintersteininger, Dandan Sun.
Lin28 overexpression inhibits neurite outgrowth of primary cortical neurons in vitro ACTA NEUROBIOLOGIAE EXPERIMENTALIS 78 4 (2018),
Mohammad Iqbal H. Bhuiyan, Seong Y. Kim, Kyung-Ok Cho.
Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke GLIA 66 1 (2018),
Gulnaz Begum, Shanshan Song, Shaoxia Wang, Hanshu Zhao, Mohammad Iqbal H. Bhuiyan, Eric Li, Rachel Nepomuceno, Qing Ye, Ming Sun, Michael J. Calderon, Donna B. Stolz, Claudette S. Croix, Yinhuai Chen, Pingnian He, Gary E. Shull, Dandan Sun.
WNK-SPAK-NKCC1 Cascade Activation Contributes to Worsened Brain Damage in Mice With Hypertension Co-Morbidity after Ischemic Stroke HYPERTENSION 72 (2018),
Mohammad Iqbal H. Bhuiyan, Huachen Huang, Ting Zhang, Bradley J. Molyneaux, Samuel M. Poloyac, Jinwei Zhang, Xianming Deng, Dandan Sun.
Presentations
SPAK inhibitor ZT-1a protects white matter integrity and improves cognitive function in mouse model of VCID (2022), Volume San Diego,
Mohammad Iqbal H. Bhuiyan.
Cyb5r3 Provides Resilience Against Cerebral Infarct And Hemorrhagic Transformation In Mice Following Stroke (2022), Volume New Orleans,
Mohammad Iqbal H. Bhuiyan.
Reducing Reactive Astrocytes Improves Cognitive Function in a Mouse Model of Vascular Cognitive Impairment and Dementia (2021), Volume Louisiana,
Mohammad Iqbal H. Bhuiyan.
SPAK/OSR1 Signaling as a Novel Target for Post-Stroke Oxidative Stress Brain Injury (2021), Volume Louisiana,
Mohammad Iqbal H. Bhuiyan.
Correlation of Ang II-induced NF-kB transcriptional activation and WNK-SPAK-NKCC1 cascade upregulation in mouse cortical neurons after ischemic stroke (2019), Volume Chicago,
Mohammad Iqbal H. Bhuiyan.
WNK-SPAK-NKCC1 cascade activation contributes to worsened brain damage in mice with hypertension comorbidity after ischemic stroke (2018), Volume Chicago,
Mohammad Iqbal H. Bhuiyan.
Grants
ASTROCYTIC WNK-SPAK-NKCC1 CASCADE IN WHITE MATTER ASTROGLIOSIS AND INJURY
Young Investigator Contest best award - The Veterans Research Foundation of Pittsburgh (01/01/2020-12/31/2020)
Young Investigator Contest best award - The Veterans Research Foundation of Pittsburgh (01/01/2019-12/31/2019)
Best poster award - Korea-Japan Joint Symposium of Society of Pharmacology (01/01/2012-12/31/2012)
Korea Research Foundation (KRF/KOSEF) Fellowship for Ph.D. study - Korea Research Foundation (KRF/KOSEF) (01/01/2004-12/31/2004)
Full scholarship by The Royal Netherlands Government for M.Sc. study - The Royal Netherlands Government (01/01/2002-12/31/2002)
Ph D in Biomolecular Science, University of Science and Technology (2010)
MS in Post-Harvest and Food Process Engineering, Asian Institute of Technology (2003)
BS in Biotechnology, Khulna University (2000)
Publications
Efficacy of novel SPAK inhibitor ZT-1a derivatives (1c, 1d, 1g & 1h) on improving post-stroke neurological outcome and brain lesion in mice NEUROCHEMISTRY INTERNATIONAL 162 (2023),
Mohammad Iqbal H. Bhuiyan, Sydney Fischer, Shivani M. Patel, Helena Oft, Ting Zhang, Lesley M. Foley, Jinwei Zhang, T. K. Hitchens, Bradley J. Molyneaux, Xianming Deng, Dandan Sun.
Near infrared spectroscopy detection of hemispheric cerebral ischemia following middle cerebral artery occlusion in rats NEUROCHEMISTRY INTERNATIONAL 162 (2023),
Ardy Wong, Mohammad Iqbal H. Bhuiyan, Jeffrey Rothman, Kelly Drew, Kambiz Pourrezaei, Dandan Sun, Zeinab Barati.
NF-kappa B Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice STROKE 53 5 (2022),
Mohammad Iqbal H. Bhuiyan, Cullen B. Young, Israt Jahan, Md Hasan, Sydney Fischer, Azlan, Nur Farah Meor, Mingjun Liu, Ansuman Chattopadhyay, Huachen Huang, Kristopher T. Kahle, Jinwei Zhang, Samuel M. Poloyac, Bradley J. Molyneaux, Adam C. Straub, Xianming Deng, Delphine Gomez, Dandan Sun.
Role of SPAK-NKCC1 signaling cascade in the choroid plexus blood-CSF barrier damage after stroke JOURNAL OF NEUROINFLAMMATION 19 1 (2022),
Jun Wang, Ruijia Liu, Md Hasan, Sydney Fischer, Yang Chen, Matt Como, Victoria M. Fiesler, Mohammad Iqbal H. Bhuiyan, Shuying Dong, Eric Li, Kristopher T. Kahle, Jinwei Zhang, Xianming Deng, Arohan R. Subramanya, Gulnaz Begum, Yan Yin, Dandan Sun.
Activation of endothelial Wnt/beta-catenin signaling by protective astrocytes repairs BBB damage in ischemic stroke PROGRESS IN NEUROBIOLOGY 199 (2021),
Shanshan Song, Huachen Huang, Xiudong Guan, Victoria Fiesler, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Shayan Jalali, Md Hasan, Albert K. Tai, Ansuman Chattopadhyay, Srilakshmi Chaparala, Ming Sun, Donna B. Stolz, Pingnian He, Dritan Agalliu, Dandan Sun, Gulnaz Begum.
Presentations
SPAK inhibitor ZT-1a protects white matter integrity and improves cognitive function in mouse model of VCID (2022), Volume San Diego,
Mohammad Iqbal H. Bhuiyan.
Cyb5r3 Provides Resilience Against Cerebral Infarct And Hemorrhagic Transformation In Mice Following Stroke (2022), Volume New Orleans,
Mohammad Iqbal H. Bhuiyan.
Reducing Reactive Astrocytes Improves Cognitive Function in a Mouse Model of Vascular Cognitive Impairment and Dementia (2021), Volume Louisiana,
Mohammad Iqbal H. Bhuiyan.
SPAK/OSR1 Signaling as a Novel Target for Post-Stroke Oxidative Stress Brain Injury (2021), Volume Louisiana,
Mohammad Iqbal H. Bhuiyan.
Correlation of Ang II-induced NF-kB transcriptional activation and WNK-SPAK-NKCC1 cascade upregulation in mouse cortical neurons after ischemic stroke (2019), Volume Chicago,
Mohammad Iqbal H. Bhuiyan.
ASTROCYTIC WNK-SPAK-NKCC1 CASCADE IN WHITE MATTER ASTROGLIOSIS AND INJURY
