UTEP Faculty Profiles

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Georgialina Rodriguez

Research Associate Professor
Biological Sciences
Border Biomedical Research Center (BBRC)

Office Building: Bioscience Research Building
Office Room: 4.132
Phone: (915) 747-8147
Email: grodriguez@utep.edu

Bio

No info available.

Education

Ph D in Cell Biology and Immunology, The University of Texas Health Science Center at Houston and M.D. Anderson Cancer Center (2008)

Publications

Phosphorylation of JAK3 SH2 domain serine 449 regulates common gamma chain cytokine signaling in human natural killer-like cells. (2023), Georgialina Rodriguez, Daniela F. Diaz, Daniel Armendariz, Omar J. Rodriguez Moncivais, Alice H. Grant, Robert A. Kirken.
Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies. (2023), Omar J. Rodriguez, Stephanie A. Chavez, Victor H. Estrada, Shengjie Sun, Lin Li, Robert A. Kirken, Georgialina Rodriguez.
Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies. International Journal of Molecular Sciences (2023), Omar J. Rodriguez, Stephanie A. Chavez, Victor H. Estrada, Shengjie Sun, Lin Li, Robert A. Kirken, Georgialina Rodriguez.
Specific Tyrosine Phosphorylation of Oncogenic JAK1 V658F Mutation Reveals New Targets for Lymphocytic Leukemia. (2023), Omar J. Rodriguez Moncivais, Victor H. Estrada, Georgialina Rodriguez, Robert A. Kirken.
JAK3 Y841 Autophosphorylation Is Critical for STAT5B Activation, Kinase Domain Stability and Dimer Formation. (2023), Georgialina Rodriguez, George S. Martinez, Omar D. Negrete, Wenhan Guo, Yixin Xie, Lin Li, Chuan Xiao, Jeremy Ross, Robert A. Kirken.
JAK3 Y841 Autophosphorylation Is Critical for STAT5B Activation, Kinase Domain Stability and Dimer Formation. International journal of molecular sciences 24 15 (2023), Georgialina Rodriguez, Gustavo Martinez, O D. Negrete, S Sun, W Guo, Yan Xie, Lin Li, Chuan Xiao, Jeremy Ross, Robert A. Kirken.
JAK3 Y841 autophosphorylation is critical for kinase domain stability and dimer formation. International Journal of Molecular Sciences (2023), Omar J. Rodriguez Moncivais, George S. Martinez, Omar D. Negrete, Shengjie Sun, Wenhan Guo, Yixin Xie, Lin Li, Aleksander C. Lazarski, Chuan Xiao, Robert A. Kirken, Georgialina Rodriguez.
Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation. (2023), Shengjie Sun, Georgialina Rodriguez, Yixin Xie, Wenhan Guo, Alan E. Lopez Hernandez, Jason E. Sanchez, Robert A. Kirken, Lin Li.
Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation Life 13 4 (2023), Shengjie Sun, Georgialina Rodriguez, Yixin Xie, Wenhan Guo, Alan E. Lopez Hernandez, Jason E. Sanchez, Robert A. Kirken, Lin Li.
Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation Life 13 4 (2023), Shengjie Sun, Georgialina Rodriguez, Yixin Xie, Wenhan Guo, Alan E. Lopez Hernandez, Jason E. Sanchez, Robert A. Kirken, Lin Li.
JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling. MDPI International Journal of Molecular Sciences (2023), Alice H. Grant, Rodriguez C. Alejandro, Rodriguez J. Omar, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling. International Journal of Molecular Sciences 24 7 (2023), Alice H. Grant, Rodriguez C. Alejandro, Rodriguez J. Omar, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling International Journal of Molecular Sciences 24 7 (2023), Alice H. Grant, Alejandro C. Rodriguez, Omar J. Rodriguez Moncivais, Shengjie Sun, Lin Li, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling International Journal of Molecular Sciences 24 7 (2023), Alice H. Grant, Alejandro C. Rodriguez, Omar J. Rodriguez Moncivais, Shengjie Sun, Lin Li, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
CRKL Association with Common Gamma Chain Receptors. (2023), Briandy Fernandez Marrero, Victor H. Estrada, Robert A. Kirken, Georgialina Rodriguez.
Development of Adenosine Receptor Over-Expressing Human Leukemia Cell Line. (2023), Luis Teran Rodriguez, Robert A. Kirken, Georgialina Rodriguez.
Identification of novel tyrosine phosphorylation sites within the pseudokinase and kinase domains of the T-cell leukemia oncogenic JAK1 V658F mutant protein. (2023), Victor Estrada, Omar J. Rodriguez Moncivais, Luis Teran Rodriguez, Briandy Fernandez Marrero, Robert A. Kirken, Georgialina Rodriguez.
Identification of novel tyrosine phosphorylation sites within the pseudokinase and kinase domains of the T-cell leukemia oncogenic JAK1 V658F mutant protein. (2023), Victor H. Estrada, Omar J. Rodriguez, Luis Teran Rodriguez, Briandy Fernandez Marrero, Robert A. Kirken, Georgialina Rodriguez.
JAK1 V666G Mutant Impairs IL-2 Signaling in Leukemia. (2023), Omar J. Rodriguez Moncivais, Alice H. Grant, Alejandro C. Rodriguez, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
JAK1 V666G Mutant Impairs IL-2 Signaling in Leukemia. (2023), Omar J. Rodriguez Moncivais, Alice H. Grant, Alejandro C. Rodriguez, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
JAK3 pS449 is induced by IL-2 and IL-15 Cytokines. (2023), Luis Teran Rodriguez, Robert A. Kirken, Georgialina Rodriguez.
Structural-Functional Analysis of JAK3 Y841 Phosphorylation. (2023), Stephanie A. Chavez, Omar J. Rodriguez Moncivais, George S. Martinez, Shengjie Sun, Wenhan Guo, Yixin Xie, Lin Li, Chuan Xiao, Robert A. Kirken, Georgialina Rodriguez.
Structural-Functional Analysis of JAK3 Y841 Phosphorylation. (2023), Stephanie A. Chavez, Omar J. Rodriguez Moncivais, George S. Martinez, Shengjie Sun, Wenhan Guo, Yixin Xie, Lin Li, Chuan Xiao, Robert A. Kirken, Georgialina Rodriguez.
JAK3 Y841 autophosphorylation is critical for kinase domain stability and dimer formation. (2023), Omar J. Rodriguez Moncivais, George S. Martinez, Omar D. Negrete, Shengjie Sun, Wenhan Guo, Yixin Xie, Lin Li, Aleksander C. Lazarski, Chuan Xiao, Robert A. Kirken, Georgialina Rodriguez.
Rapid shift from SARS-Cov-2 Delta to Omicron sub-variants within a dynamic southern U.S. borderplex Viruses (2023), Elisa Robles, Jonathon E. Mohl, Lisett Contreras, Ana P. Betancourt, Bibiana M. Mancera, Robert A. Kirken, Georgialina Rodriguez.
Rapid Shift from SARS-CoV-2 Delta to Omicron Sub-Variants within a Dynamic Southern U.S. Borderplex. Viruses 15 3 (2023), E Robles-Escajeda, Jonathon E. Mohl, L Contreras, A P. Betancourt, Bibiana M. Mancera, Robert A. Kirken, Georgialina Rodriguez.
Phosphoproteomic Analysis of Janus Kinase 3. (2022), Conrad Bencomo, Georgialina Rodriguez, Robert A. Kirken.
Characterization of Jak3 SH2 Domain Serine Phosphorylation. (2022), Carolina Quintana, Georgialina Rodriguez, America Y. Alvidrez Camacho, Daniela F. Diaz, Daniel Armendariz, Alice H. Grant, Chuan Xiao, Robert A. Kirken.
JAK1 Psuedokinase Mutation HiJAKs Tyr Phosphorylation. (2022), Elisa Robles Escajeda, Alice H. Grant, Georgialina Rodriguez, Alejandro C. Rodriguez, Aleksander Lazarski, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken.
Phosphotyrosine-γc Facilitates CrkL-IL2 Signaling Cascade. (2022), Omar J. Rodriguez Moncivais, Georgialina Rodriguez, Yoshira M. Ayala Marin, Armando Estrada III, Robert A. Kirken.
tructure-Function of Novel JAK Autophosphorylation Sites. (2022), Georgialina Rodriguez, George S. Martinez, Omar D. Negrete, Shengjie Sun, Wenhan Guo, Yixin Xie, Lin Li, Aleksander Lazarski, Chuan Xiao, Robert A. Kirken.
Quadruple and Truncated MEK3 Mutants Identified from Acute Lymphoblastic Leukemia Promote Degradation and Enhance Proliferation. International journal of molecular sciences 22 22 (2021), Y M. Ayala-Marin, A H. Grant, Georgialina Rodriguez, Robert A. Kirken.
Establishing a Mechanism of Tumor Evasion Through Adenosine Receptor Cross-talk with Common Gamma Chain Signing in Immune Cells. (2021), America Y. Alvidrez Camacho, Georgialina Rodriguez, Conrad Bencomo, Robert A. Kirken.
Regulation of Common Gamma Chain and JAK3 Pathway Signaling by Adenosine Receptor Cross-talk. (2021), America Y. Alvidrez Camacho, Georgialina Rodriguez, Conrad Bencomo, Robert A. Kirken.
Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction. Scientific reports 11 1 (2021), A Estrada, A C. Rodriguez, Georgialina Rodriguez, A H. Grant, Y M. Ayala-Marin, A J. Arrieta, Robert A. Kirken.
Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction. Scientific Reports 11 1695 (2021), Armando Estrada, Alejandro C. Rodriguez, Georgialina Rodriguez, Alice H. Grant, Yoshira M. Ayala-Marin, Amy J. Arrieta, Robert A. Kirken.
The Many Faces of JAKs and STATs Within the COVID-19 Storm. Frontiers in immunology 12 (2021), A H. Grant, A Estrada, Y M. Ayala-Marin, A Y. Alvidrez-Camacho, Georgialina Rodriguez, E Robles-Escajeda, D A. Cadena-Medina, A C. Rodriguez, Robert A. Kirken.
The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border. International journal of environmental research and public health 18 14 (2021), A H. Grant, Y M. Ayala-Marin, Jonathon E. Mohl, E Robles-Escajeda, Georgialina Rodriguez, J Dutil, Robert A. Kirken.
The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border International Journal of Environmental Research and Public Health 18 14 (2021), Alice Hernandez Grant, Yoshira M. Ayala-Marin, Jonathon E. Mohl, Elisa Robles Escajeda, Georgialina Rodriguez, Julie Dutil, Robert A. Kirken.
The Many Faces of JAKs and STATs Within the COVID-19 Storm Frontiers in Immunology 12:690477 (2021), Alice H. Grant, Armando Estrada, Yoshira M. Ayala-Marin, America Y. Alvidrez-Camacho, Georgialina Rodriguez, Elisa Robles Escajeda, Denisse A. Cadena-Medina, Alejandro C. Rodriguez, Robert A. Kirken.
Elucidation of Tyrosine Phosphorylation Sites within IL2-Ryc Using Customized Phospho-Specific Antibodies. (2021), Karla Damian, Yoshira M. Ayala Marin, Georgialina Rodriguez, Robert A. Kirken.
Establishing a Mechanism of Tumor Evasion Through Adenosine Receptor Cross-talk with Common Gamma Chain Signing in Immune Cells American Society for Microbiology/Annual Biomedical Research Conference for Minority Students (in press), America Y. Alvidrez-Camacho, Georgialina Rodriguez, Conrad Bencomo, Robert A. Kirken.
Regulation of Common Gamma Chain and JAK3 Pathway Signaling by Adenosine Receptor Cross-talk Gulf Coast Undergraduate Research Symposium (in press), America Y. Alvidrez-Camacho, Georgialina Rodriguez, Conrad Bencomo, Robert A. Kirken.
The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border International Journal of Environmental Research and Public Health 18 14 (2021), Alice H. Grant, Yoshira M. Ayala-Marin, Jonathon E. Mohl, Elisa Robles-Escajeda, Georgialina Rodriguez, Julie Dutil, Robert A. Kirken.

Presentations

JAK1 V666G Mutant Impairs Il-2 Signaling In Leukemia (2023), Omar J. Rodriguez Moncivais, Alice H. Grant, A C. Rodriguez, S Sun, L Lin, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
Structure-Function Relationship of Novel Phosphoregulatory Sites and Effect of Acute Lymphoblastic Leukemia SNPs on Jak3 Activity: Implications for new cancer treatments (2021), Volume Virtual, Georgialina Rodriguez.

Grants

Cancer Health Disparities that Impact El Paso Community

Current/Future Courses

No info available.

Past Courses

No info available.

Course Evaluations

No info available.

Bio

No info available.

Ph D in Cell Biology and Immunology, The University of Texas Health Science Center at Houston and M.D. Anderson Cancer Center (2008)

Publications

Phosphorylation of JAK3 SH2 domain serine 449 regulates common gamma chain cytokine signaling in human natural killer-like cells. (2023), Georgialina Rodriguez, Daniela F. Diaz, Daniel Armendariz, Omar J. Rodriguez Moncivais, Alice H. Grant, Robert A. Kirken.
Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies. (2023), Omar J. Rodriguez, Stephanie A. Chavez, Victor H. Estrada, Shengjie Sun, Lin Li, Robert A. Kirken, Georgialina Rodriguez.
Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies. International Journal of Molecular Sciences (2023), Omar J. Rodriguez, Stephanie A. Chavez, Victor H. Estrada, Shengjie Sun, Lin Li, Robert A. Kirken, Georgialina Rodriguez.
Specific Tyrosine Phosphorylation of Oncogenic JAK1 V658F Mutation Reveals New Targets for Lymphocytic Leukemia. (2023), Omar J. Rodriguez Moncivais, Victor H. Estrada, Georgialina Rodriguez, Robert A. Kirken.
JAK3 Y841 Autophosphorylation Is Critical for STAT5B Activation, Kinase Domain Stability and Dimer Formation. (2023), Georgialina Rodriguez, George S. Martinez, Omar D. Negrete, Wenhan Guo, Yixin Xie, Lin Li, Chuan Xiao, Jeremy Ross, Robert A. Kirken.

Presentations

JAK1 V666G Mutant Impairs Il-2 Signaling In Leukemia (2023), Omar J. Rodriguez Moncivais, Alice H. Grant, A C. Rodriguez, S Sun, L Lin, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez.
Structure-Function Relationship of Novel Phosphoregulatory Sites and Effect of Acute Lymphoblastic Leukemia SNPs on Jak3 Activity: Implications for new cancer treatments (2021), Volume Virtual, Georgialina Rodriguez.

Cancer Health Disparities that Impact El Paso Community

Current/Future Courses

No info available.

Past Courses

No info available.

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Georgialina Rodriguez

FACULTY PROFILES

Georgialina Rodriguez

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