Researcher Interested in studying the Biology of Metastasis

• Best Poster ABRCMS (Joe Wingate) - ABRCMS (11/01/2019)
• UTEP Academy Distinguished Teachers - University of Texas at El Paso (05/10/2019)
• UT Academy Distinguished Teachers - UT System (05/05/2019)
• 2018 ROTA Award ($25,000) (08/01/2018-08/31/2018)
• ROTA UTEP Nominee (08/01/2017-08/31/2017)
• Best Poster ABRCMS (Student; Jonathan Prieto) (11/01/2016-11/30/2016)
• ROTA Departmental Nominee (08/01/2016-08/31/2016)
• Invited Speaker (SABC Breast Cancer Oncology Educational Session) - prIME Oncology (12/01/2015-12/31/2015)
• Physics Departmental Award for Academic & Research Excellence (12/01/2015-12/31/2015)
• Best Poster ABRCMS (Student; Diana G. Garcia) (11/01/2015-11/30/2015)
• Best TA in Biology Department (05/01/2015-05/31/2015)
• Invited Speaker - Haifa, Israel (05/01/2015-05/31/2015)
• ROTA Departmental Nominee (12/01/2014-12/31/2014)
• UTEP Nomination for ROTA teaching Award 2014 - ROTA (10/01/2014-10/31/2014)
• Invited Speaker, Zurich (Switzerland) Symposium on Translational Animal Research - - Collegium Helveticum (11/20/2013)
• SACNAS Travel Scholarship - SACNAS (10/11/2012)
• ASCB MAC Travel Award - Minorities Affairs Committee (09/25/2012)
• UTEP Summer Research Experience for Undergraduates in Molecular and Cellular Biology - UTEP Dept. of Biological Sciences (05/26/2012)
• NIH Early Career Reviewer, Tumor Progression and Metastasis Study Section (02/01/2012-02/28/2012)
• 2012 ASCB MAC Junior Faculty and Postdoctoral Fellows Career Development Workshop Travel Award

• Ph D in Biology, ICRF/Kings College London (1998)
• BS in Biology, University of Bristol (1994)

• ErbB2/Her2-dependent downregulation of a cell death-promoting protein BLNK in breast cancer cells is required for 3D breast tumor growth (2022), Liu et al, Giulio Francia, Kerbel RS, Rosen KV.
• Cyclic Metronomic Chemotherapy for Pediatric Tumors: Six Case Reports and a Review of the Literature J Clin Med . 2022 May 18;11(10):2849. doi: 10.3390/jcm11102849. (2022), Carcamo, Giulio Francia.
• Impact of host stroma on the anti-tumor effects of metronomic chemotherapy. SACNAS National Diversity in STEM Conference: October 2022; San Juan, PR. (2022), Ronquillo, Giulio Francia.
• Impact of stromal components in tumors responding to metronomic chemotherapy. COURI Spring Symposium: April 2022; El Paso, TX (2022), Ronquillo, Giulio Francia.
• Metronomic Gemcitabine for Breast Cancer Brain Metastases. UTEP COURI August 2022. (2022), Padilla, Giulio Francia.
• The role of stroma on the anti-tumor effects of metronomic cyclophosphamide. COURI Summer Symposium: August 2022; El Paso, (2022), Ronquillo, Giulio Francia.
• Metronomic chemotherapy and anti-angiogenic drugs: Preclinical and clinical data.Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Vol 19 (in Press) (2021), Bocci, Giulio Francia, Serina Batson.
• Production of Monoclonal Antibodies- Tubulin, Meca32, and C44-using Cell Culture Technology ABRCMS (Annual Biomedical Research Conference for Minority Students), Virtual Conference, Nov 2021. (2021), Jazmin Corral, Giulio Francia.
• BEST Poster AWARD "Continuous Low Dose Gemcitabine Chemotherapy " ABRCMS 2021 Virtual Conference Nov 10-13 (2021), Arlene Levario, Giulio Francia.
• Production of Monoclonal Antibodies- Tubulin, Meca32, and C44-using Cell Culture Technology Symposium for Undergraduate Research Exploration, University of Texas at Austin, Oct 2021. (2021), Jazmin Corral, Giulio Francia.
• Pharmacodynamic biomarkers in metronomic chemotherapy: Multiplex cytokine measurements in gastrointestinal cancer patients Clinical and Experimental Medicine (2021), Paloma Valenzuela, Derrick Oaxaca, Teresa Di Desidero, Karla Parra, Georgialina Rodriguez, Marian M. Manciu, Giacomo Allegrini, Alfredo Falcone, , Guido Bocci, Robert A. Kirken, , Giulio Francia.
• Pharmacodynamic biomarkers in metronomic chemotherapy: multiplex cytokine measurements in gastrointestinal cancer patients Clin Exp Med. 2021 Feb;21(1):149-159. doi: 10.1007/s10238-020-00666-9. (2021), Valenzuela P et al, Oaxaca D, Parra K, Kirken RA, Giulio Francia.
• Development of a VLP-Based Vaccine Displaying an xCT Extracellular Domain for the Treatment of Metastatic Breast Cancer Cancers (Basel) . 2020 Jun 8;12(6):1492. doi: 10.3390/cancers12061492. (2020), Rolih V et al, Giulio Francia, Cavallo, F.
• Synergistic activity of linifanib and irinotecan increases the survival of mice bearing orthotopically implanted human anaplastic thyroid cancer Am J Cancer Res . 2020 Jul 1;10(7):2120-2127. eCollection 2020. (2020), Banchi M et al, Giulio Francia, Bocci, G.
• Pre-clinical Evaluation of Gemcitabine’s efficacy in treating Breast Cancer Brain Metastases NIH Diversity Program Consortium (2020), Wingate, Giulio Francia.
• Pharmacological effects of vinorelbine in combination with lenvatinib in anaplastic thyroid cancer Pharmacol Res. 2020 Aug;158:104920. doi: 10.1016/j.phrs.2020.104920. Epub 2020 May 24. (2020), Di Desidero et al, Cayme G, Giulio Francia, Bocci, G.
• Overexpression of p62/IMP2 can promote cell migration in hepatocellular carcinoma via activating Wnt/β-catenin pathway. Cancers 12 1 (2020), Mengtao Xing, Xiao Wang, Jitian Li, Xiaojun Zhang, Yangcheng Ma, Giulio Francia, Jianying Zhang.
• Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/ β-Catenin Pathway Cancers (Basel). 2019 Dec 18;12(1):7. doi: 10.3390/cancers12010007. (2019), Mengtao Xing, Giulio Francia, Jianying Zhang.
• Intracranial breast cancer model (2019), Joseph Wingate et al, Giulio Francia.
• Optimization of biomarkers-based classification scores as progression free survival predictors: an intuitive graphical representation Future Science Open Access 4 10 (2018), Marian M. Manciu, Sorour Hosseini, Teresa Desidero, Giacomo Allegrini, Alfredo Falcone, Guido Bocci, Robert A. Kirken, Giulio Francia, , , .
• Optimization of biomarkers-based classification scores as progression free survival predictors: an intuitive graphical representation Future Science Open Access 4 10 (2018), Marian M. Manciu, Sorour Hosseini, Teresa Desidero, Giacomo Allegrini, Alfredo Falcone, Guido Bocci, Robert A. Kirken, Giulio Francia, , , .
• Precision therapeutic targeting of human cancer cell motility. Nat Commun. 2018 Jun 22;9(1):2454. doi: 10.1038/s41467-018-04465-5. (2018), L Xu, Giulio Francia, R Bergan.
• Metronomic vinorelbine is active on EGFRwt and EGFRL858R/T790M Non Small Cell Lung Cancer cells, alone and in combination with EGFR tyrosine kinase inhibitors Biochem Pharmacol. 2018 Jun;152:327-337. doi: 10.1016/j.bcp.2018.04.011. Epub 2018 Apr 13. PMID: 29660315 (2018), P Orlandi, T Di Desidero, C Salvia, B Muscatello, Giulio Francia, G Bocci.
• Spatiotemporal assessment of spontaneous metastasis formation using multimodal in vivo imaging in HER2+ and triple negative metastatic breast cancer xenograft models in mice. PLoS One . 2018 May 3;13(5):e0196892. doi: 10.1371/journal.pone.0196892. eCollection 2018. (2018), IB Fricke, Giulio Francia.

• Impact of gemcitabine chemotherapy regimens on breast cancer brain metastases (2020), Levario, Giulio Francia.
• AAA12 Paclitaxel Directed Screening to identify novel anti-cancer drugs (2020), Wingate J, Diana Gonzalez et al, Giulio Francia.
• From Experimental therapeutics to Paclitaxel directed drug screening (2019), Giulio Francia.
• Devising therapeutic strategies for metastatic breast cancer (2019), Giulio Francia.
• Overexpression of p62/IMP2 can promote cell migration in hepatocellular carcinoma (HCC) via activating Wnt/β-catenin pathway. (2019), Volume Atlanta, Georgia, Mengtao Xing, Giulio Francia, Jianying Zhang.
• Overexpression of p62/IMP2 can promote cell migration in hepatocellular carcinoma (HCC) via activating Wnt/β-catenin pathway. (2019), Volume Atlanta, Georgia, Mengtao Xing, Giulio Francia, Jianying Zhang.
• Novel Drug Identification for Biomarker Tagged Triple Negative Breast Cancer Cells to Study Pre-clinical Brain Metastases (2019), Wingate, J et al, Giulio Francia.
• Surgical involvement in Colorectal Cancer in Mice Models and the Effects of Gemcitabine in Colorectal Metastasis (2019), Sanchez E et al, Giulio Francia.
• Label-Free Raman Imaging to Monitor Breast Tumor Signatures (2018), Volume El Paso, John D. Ciubuc, Giulio Francia, Marian M. Manciu, Karla Parra, Kevin E. Bennet, Emma M. Sundin, Paloma Valenzuela, Felicia S. Manciu.
• The Pursuit of Label‐free Breast Cancer Detection (2018), Volume El Paso, Felicia S. Manciu, Giulio Francia.
• Label-Free Raman Imaging to Monitor Breast Tumor Signatures (2018), Volume El Paso, TX, John D. Ciubuc, Giulio Francia, Marian M. Manciu, Karla Parra, Kevin E. Bennet, Emma M. Sundin, Pamela Valenzuela, Felicia S. Manciu.
• Metronomic Chemotherapy-Based Regimens: Combination Versus Sequential Administration (2018), Volume Gran Rapids, Michigan, Giulio Francia.
• Optimization of biomarkers-based classification scores as Progression Free Survival predictors: An intuitive graphical representation (2018), Volume Grand Rapids, Michigan, Marcos Amendariz, Karla Parra, Paloma Valenzuela, Sorour Hosseini, Teresa Di Desidero, Giacomo Allegrini, Alfredo Falcone, Guido Bocci, Robert A. Kirken, Giulio Francia, Marian M. Manciu.
• Optimization of biomarkers-based classification scores as Progression Free Survival predictors: An intuitive graphical representation (2018), Volume Grand Rapids, Michigan, Marcos Amendariz, Karla Parra, Paloma Valenzuela, Sorour Hosseini, Teresa Di Desidero, Giacomo Allegrini, Alfredo Falcone, Guido Bocci, Robert A. Kirken, Giulio Francia, Marian M. Manciu.
• Pharmacodynamics and pharmacogenomics of metronomic vinorelbine in human endothelial cells (2018), Volume Grand Rapids, Michigan , Ivan Sosa, Karla Parra, Paola Orlandi, Teresa Di Desidero, Paloma Valenzuela, Karen Chavez, Diana Gonzalez, Joel Martinez, Felicia S. Manciu, Marian M. Manciu, Giulio Francia, Guido Bocci.
• Pharmacodynamics and pharmacogenomics of metronomic vinorelbine in human endothelial cells (2018), Volume Michigan, Ivan Sosa, Karla Parra, Paola Orlandi, Teresa Di Desidero, Paloma Valenzuela, Karen Chavez, Diana Gonzalez Garcia, Joel Martinez, Felicia S. Manciu, Marian M. Manciu, Giulio Francia, Guido Bocci.
• Pharmacodynamics and pharmacogenomics of metronomic vinorelbine in human endothelial cells (2018), Volume Grand Rapids, Michigan , Ivan Sosa, Karla Parra, Paola Orlandi, Teresa Di Desidero, Paloma Valenzuela, Karen Chavez, Diana Gonzalez, Joel Martinez, Felicia S. Manciu, Marian M. Manciu, Giulio Francia, Guido Bocci.
• P62/IMP2 Promotes metastasis in hepatocellular carcinoma (HCC) by regulating EMT in different signaling pathway. (2018), Volume Chicago, Mengtao Xing, Jitian Li, Giulio Francia, Jianying Zhang.
• P62/IMP2 Promotes metastasis in hepatocellular carcinoma (HCC) by regulating EMT in different signaling pathway. (2018), Volume Chicago, Mengtao Xing, Jitian Li, Giulio Francia, Jianying Zhang.

• SC1 SCORE : The role of breast cancer organ specific metastasis on the therapeutic impact of anti-cancer drugs
• Single cell RNA sequencing
• Paclitaxel Directed Drug Screening; a new strategy to identify anti-cancer drugs (SC2 SCORE)
• High time for changing the treatment paradigms and unraveling the therapeutic tangle in anaplastic thyroid cancer