Dr. Spencer's research focuses on translational studies of the immune response to bacteria (e.g., Francisella spp., Mycobacteria spp. and Listeria) incorporating his experience with both mouse and human experimental systems to extrapolate and validate observations made in animals in order to better understand and manipulate the human immune response to pathogens and vaccines.

• Edward and Barbara Brown Egbert Endowed Associate Chair in Biological Sciences (08/17/2020)
• Tenure - University of Texas at El Paso (09/01/2018)
• UT-ROTA College of Science nominee (06/22/2015)
• AAI Undergraduate Faculty Travel Award - American Association of Immunologists (05/01/2015-05/31/2015)
• ABRCMS Travel Subsidy - ASM ABRCMS (10/08/2013)
• COURI Research Award - UTEP-COURI (09/15/2013)
• ASCB MAC 2013 8th Annual Junior Faculty/Postdoctoral Fellows Career Development Workshop Travel Award - American Society for Cell Biology Minorities Affairs Committee (05/16/2013)

• Ph D in Molecular Microbiology and Immunology, Saint Louis University (2008)
• BA in Biology, Washington University in St. Louis (2000)

• Infection Control Program Among the Ysleta del Sur Pueblo Prevents Hospitalizations and Deaths During the Covid-19 Pandemic Pathogens 2024 13 (2024), Cameron Torres, Victoria Aparicio, Gabriela Morales, Ascension Mena, Charles Spencer.
• The association of allostasis with alcohol use disorders: a case-control study in males with and without alcohol use disorder Alcohol (2023), Carlos Portillo, Bryon Adinoff, Charles T. Spencer, Craig A. Field.
• Computational and Systems Biology Advances to Enable for Bioagent Agnostic Signatures Health Security (2023), Andy Lin, Cameron Torres, Errett C. Hobbs, Jaydeep Bardhan, Stephen B. Aley, Charles Spencer, Karen L. Taylor, Tony Chiang.
• Alcohol self-administration and nicotine withdrawal alter biomarkers of stress and inflammation and prefrontal cortex changes in Gβ subunits The American Journal of Drug and Alcohol Abuse 0 0 (2022), Bryan Cruz, Karen Castañeda, Michelle Aranda, Cecilia A. Hinojosa, Roberto Castro-Gutierrez, Rodolfo J. Flores, Charles Spencer, Valentina Vozella, Marisa Roberto, Bharathi S. Gadad, Sukla Roychowdhury, Laura E. O'Dell.
• Francisella tularensis Infection of Mice as a Model of Sepsis Springer (2021), Charles Spencer, Mireya G. Ramos Muniz, Nicole Setzu, Michelle A. Sanchez.

• Intranasal STING-formulated nanoparticle vaccine elicits protective immunity against Mycobacterium tuberculosis (2023), Volume San Antonio TX, Samiur Rahman Sefat, Monish Kumar, Stephanie Kehl, Ankita Leekha, Melisa Martinez Peniagua, Nicole Jones, Charles Spencer, Hugues Ouellet, Navin Varadarajan.
• Proteomics Study of Oligodendrocyte in Postmortem Brain from Subjects with Major Depressive Disorder and Suicidality (2023), Volume TTUHSCEP, Javier Vargas, Charles Spencer, Enrique I. Ramos, Alejandra Ruiz-Velasco, Peter M. Thompson, Bharathi S. Gadad.
• Brain-Cell Type Proteomics Analyses Specific to Oligodendrocyte in Postmortem Brain Subjects With Major Depressive Disorder and Suicidality (2023), Volume San Diego, CA, Javier Vargas Medrano, Charles Spencer, Enrique Ramos, Alejandra Ruiz-Velasco, Andrew Lemoff, Peter Thompson, Bharathi Gadad.
• Alginate Based ZnO Nanoparticle Scaffolds for Wound Healing (2020), Volume UCLA, Carol M. Cleetus, Gisel Fregoso, Fabian Alvarez-Primo, Nivedita L. Raveendran, Shane C. Allen, Juan C. Noveron, Charles Spencer, Chintallapalle V. Ramana, Binata Joddar.
• NKT cell subsets and their roles during infection caused by Francisella tularensis (2019), Leslie Rodriguez, Charles Spencer.

• NKT cell subsets modulate systemic inflammation