I am a broadly trained computational biologist with expertise in Molecular Biology, Genomics, and Bioinformatics. My research involves the utilization of in-silico, in-vitro, and in-vivo methodologies for understanding gene regulation.

• Ph D in Genomics and Bioinformatics , University of California Riverside (2011)
• MS in Bioinformatics, Indiana University Bloomington (2006)
• Information Technology, All India Management Association (2001)
• MS in Zoology (Specialization in Genetics), University of Kalyani (1998)
• BS in Zoology, University of Calcutta (1996)

• Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy. PLoS neglected tropical diseases 17 3 (2023), P Silva Grijó Farani, B da Iandra Silva Ferreira, K Begum, G Vilar-Pereira, I R. Pereira, E A. Fernández-Figueroa, R A. Cardenas-Ovando, Igor C. Almeida, Sourav Roy, J Lannes-Vieira, O C. Moreira.
• Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms Scientific Reports 13 1 (2023), Myriah L. Acuña, Andrea García-Morin, Rebeca Orozco-Sepúlveda, Carlos Ontiveros, Alejandra Flores, Arely V. Diaz, Isabel Gutiérrez-Zubiate, Abhijeet R. Patil, Luis A. Alvarado, Sourav Roy, William K. Russell, Germán Rosas-Acosta.
• Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms Scientific Reports 13 2309 (2023) (2023), Myriah L. Acuna, Andrea T. Garcia, Rebeca Orozco, Carlos Ontiveros, Alejandra Flores, Arely Diaz, Isabel Gutierrez-Zubiate, Abhijeet R. Patil, Luis A. Alvarado, Sourav Roy, William K. Russell, German Rosas-Acosta.
• tructure and function of the TPR-domain immunophilins FKBP51 and FKBP52 in normal physiology and disease Journal of Cellular Biochemistry (2023), Olga B. Soto, Christian S. Ramirez, Rina Koyani, Isela A. Rodriguez-Palomares , Jessica R. Dirmeyer, Brian I. Grajeda, Sourav Roy, Marc B. Cox.
• Alternative splicing of the SUMO transcripts contributes to the regulation of the cellular SUMOylation system and produces messages coding for protein isoforms functionally distinct from the prototypical SUMO proteins Research Square (2022), Myriah L. Acuna, Andrea T. Garcia, Rebeca Orozco, Carlos Ontiveros, Alejandra Flores, Arely Diaz, Isabel Gutierrez-Zubiate, Abhijeet R. Patil, Luis A. Alvarado, Sourav Roy, William K. Russell, German Rosas-Acosta.
• Giardial lipid rafts share virulence factors with secreted vesicles and participate in parasitic infection in mice Front Cell Infect Microbiol 12 (2022), Grajeda I. Brian, Atasi De Chatterjee, Carmen M. Villalobos, Breanna C. Pence, Cameron C. Ellis, Venessa Enriquez, Sourav Roy, Sukla Roychowdhury, Arron K. Newmann, , Igor C. Almeida, Steven E. Patterson, Siddhartha Das.
• Giardial lipid rafts share virulence factors with secreted vesicles and participate in parasitic infection in mice. Frontiers in Cellular and Infection Microbiology Frontiers in Cellular and Infection Microbiology 12 (2022), B I. Grajeda, A De Chatterjee, C M. Villalobos, B C. Pence, Carla Ellis, V Enriquez, Sourav Roy, Sukla Roychowdhury, A K. Neumann, Igor C. Almeida, Samantha Patterson, Siddhartha Das.
• Regulatory Roles of Noncoding RNAs in the Progression of Gastrointestinal Cancers and Health Disparities. Cells 11 15 (2022), A Kulkarni, S Gayathrinathan, S Nair, A Basu, Taslim A. Al-Hilal, Sourav Roy.
• Diversifying the genomic data science research community Genome Research # Corresponding Author 32 7 (2022), Genomic Data Science Community Network , Sourav Roy.
• Eight weeks of combined exercise training do not alter circulating microRNAs-29a, -133a, -133b, and -155 in young, healthy men. European journal of applied physiology 122 4 (2022), C A. Meza, M Amador, A J. McAinch, K Begum, Sourav Roy, Sudip Bajpeyi.
• Direct and indirect gene repression by the ecdysone cascade during mosquito reproductive cycle PNAS # Corresponding Author 119 11 (2022), Sourav # Roy, Tusar T. Saha, Jisu Ha, Raumik Banerjee, Emre Aksoy, Aditi Kulkarni, Alexander # S. Raikhel.
• Cancer-on-a-Chip: Models for Studying Metastasis. Cancers 14 3 (2022), X Zhang, Mohammad A. Karim, Md Hasan, J Hooper, R Wahab, Sourav Roy, Taslim A. Al-Hilal.
• Cancer-on-a-Chip: Models for Studying Metastasis. Cancers 14 3 (2022), Xiaojun Zhang , Mazharul Karim, Md M. Hasan , Jacob Hooper, Riajul Wahab , Sourav Roy, Taslim A. Al-Hilal.
• Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways Cells 11 2 (2022), Denisse A. Gutierrez, Lisett Contreras, Paulina J. Villanueva, Edgar A. Borrego, Karla Morán-Santibañez, Jessica D. Hess, Rebecca DeJesus, Manuel Larragoity, Ana P. Betancourt, Jonathon E. Mohl, Elisa Robles-Escajeda, Khodeza Begum, Sourav Roy, Robert A. Kirken, Armando Varela-Ramirez, Renato Aguilera.
• Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways Cells 11 2 (2022), Denisse A. Gutierrez, Lisett Contreras, Paulina J. Villanueva , Edgar A. Borrego, Karla Morán-Santibañez, Jessica D. Hess, Rebecca DeJesus, Manuel Larragoity , Ana P. Betancourt, Jonathon E. Mohl , Elisa Robles-Escajeda, Khodeza Begum, Sourav Roy, Robert A. Kirken, Armando Varela-Ramirez, Renato J. Aguilera.
• Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways. Cells 11 2 (2022), D A. Gutierrez, L Contreras, P J. Villanueva, E A. Borrego, K Morán-Santibañez, J D. Hess, R DeJesus, M Larragoity, A P. Betancourt, Jonathon E. Mohl, E Robles-Escajeda, K Begum, Sourav Roy, Robert A. Kirken, A Varela-Ramirez, Renato Aguilera.
• Eight weeks of combined exercise training do not alter circulating microRNAs- 29a, -133a, -133b, and -155 in young healthy men. Eur J Appl Physiol (2022), Cesar A. Meza, Manuel Amador , Andrew J. McAinch, Khodeza Begum, Sourav Roy, Sudip Bajpayi.
• The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells Cells 10 10 (2021), Greisha L. Ortiz-Hernandez, Evelyn S. Sanchez-Hernandez, Pedro T. Ochoa, Catherine C. Elix, Hossam R. Alkashgari , James R. McMullen, Ubaldo Soto, Shannalee R. Martinez, Carlos J. Osterman, Michael Mahler , Sourav Roy, Carlos A. Casiano.
• Differential Expression of Non-Coding RNA Signatures in Thyroid Cancer between Two Ethnic Groups. Current Oncology # Corresponding Author 28 5 (2021), Kristiana M M. Rood, Kohdeza Begum, Hanmin Wan, Yan C. Wangworawat, Ryan S. Davis, Celena R. Yamaguchi, Mia Perez, Alfred A. Simental, Ria T. Laxa, Charles Wang, Sourav # Roy , Salma # Khan .
• Treatment with Suboptimal dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice with Chronic Chagasic Cardiomyopathy Front Cell Infect Microbiol 11 (2021), Priscila S. Grijó Farani, Khodeza Begum, Glaucia Vilar-Pereira, Isabela R. Pereira , Igor C. Almeida, Sourav Roy, Joseli Lannes-Vieira, Otacilio C. Moreira.
• Identification of Hub Genes in Different Stages of Colorectal Cancer through an Integrated Bioinformatics Approach. Int J Environ Res Public Health # Corresponding Author 18 11 (2021), Abhijeet R. Patil, Ming-Ying Leung, Sourav # Roy.
• Identification of Hub Genes in Different Stages of Colorectal Cancer through an Integrated Bioinformatics Approach Int. J. Environ. Res. Public Health 18 (2021), Abhijeet R. Patil, Ming-Ying Leung, Sourav Roy.
• A role of stress-survival pathway and apoptosis in progression of colorectal cancer – a health disparities perspective Int J Environ Res Public Health. # Corresponding Author 18 11 (2021), Urbashi Basnet, Abhijeet R. Patil, Aditi V. Kulkarni, Sourav # Roy.
• Synergistic action of the transcription factors Krüppel homolog 1 and Hairy in juvenile hormone/Methoprene-tolerant-mediated gene-repression in the mosquito Aedes aegypti. PLoS Genetics. 15 10 (2019), Tusar + Saha, Sourav + Roy, Gaofeng Pei, Wei Dou, Zhen Zou, Alexander S. Raikhel.

• AnVIL/Velsera-CGC interoperability project to study the genetic and transcriptomic contributions towards Hispanic colorectal cancer health disparities (2023), Volume Online, Sourav Roy.
• Deciphering the roles of the two ecdysone-induced protein E74 isoforms as intermediate factors in the 20E-EcR gene regulatory cascade in mosquito reproduction (2023), Volume Riverside California, Sharan Gayathrinathan, Frida Delgadillo, Sourav Roy.
• Differential expression of stress-survival pathway genes related to Hispanic colorectal cancer disparities (2023), Volume Interdisciplinary Research Building, UTEP, Sourav Roy.
• Transcriptomic profiling of Hispanic colorectal cancer disparities (2023), Volume Orlando, Florida, Soumya Nair, Aditi Kulkarni, Brian I. Grajeda, Sourav Roy.
• Opportunities in Computational Biology (2023), Volume UTEP, Sourav Roy.
• Differential expression of stress-survival pathway genes related to Hispanic colorectal cancer disparities. (2023), Volume Orlando, Florida, Urbashi Basnet, Aditi Kulkarni, Frances Rangel, Abhijeet R. Patil, Sourav Roy.
• Genes and pathways related to Hispanic colorectal cancer disparities (2023), Volume Orlando, Florida, Urbashi Basnet, Aditi Kulkarni, Soumya Nair, Brian I. Grajeda, Sourav Roy.
• Use of Bioinformatics in Biological Sciences (2023), Volume UTEP, Sourav Roy.
• An ascitic fluid-derived organoid platform for hispanic ovarian cancer patients to capture heterogeneity and disparity (2023), Volume Orlando, Florida, MD Mynul Hassan, SM Riajul Wahab, Sheralyn Sanchez, Eugene Toy, Sireesha Y. Reddy, Sourav Roy, Taslim A. Al-Hilal.
• Differential expression of stress-survival pathway genes related to Hispanic colorectal cancer disparities (2023), Volume San Antonio, Texas, Sourav Roy.
• Differential expression of stress-survival pathway genes related to Hispanic colorectal cancer disparities (2022), Volume UTEP, Urbashi Basnet, Aditi Kulkarni, Frances Rangel, Sourav Roy.
• Differential Expression of Stress Survival Pathway Genes in Colorectal Cancer (2022), Volume Puerto Rico, Frances Rangel, Aditi Kulkarni, Urbashi Basnet, Sourav Roy.
• Use of Bioinformatics in Biological Sciences (2022), Volume UTEP, Sourav Roy.
• Differential expression of stress survival pathway genes in colorectal cancer cell lines (2022), Volume UTEP, Frances Rangel, Aditi Kulkarni, Urbashi Basnet, Sourav Roy.
• Role of stress-survival pathways and transcriptomic alterations in progression of colorectal cancer: A Hispanic health disparities perspective (2022), Volume Philadelphia, PA, Sourav Roy, Aditi Kulkarni, Urbashi Basnet, Frances Rangel.
• Gene regulatory elements and networks provide an insight into direct and indirect negative regulation by the ecdysone cascade (2022), Volume Helsinkii, Finland, Sourav Roy, Kulkarni Aditi, Tusar T. Saha, Alexander S. Raikhel.
• An Indian American Computational Biologist in One of the Largest and Most Successful Hispanic Serving Institutions in the Country (2022), Volume Online, Sourav Roy.
• Differential expression of macrophages in gastric antral smooth muscle of patients with idiopathic gastroparesis compared to diabetic etiology (2022), Vikram Thakur, Sourav Roy, Brian Davis, Irene Sarosiek, Richard McCallum, Munmun Chattopadhyay.
• Differential expression of stress survival pathway genes in colorectal cancer cell lines (2022), Volume UTEP, Frances Rangel, Aditi Kulkarni, Urbashi Basnet, Sourav Roy.
• Opportunities in Computational Biology (2022), Volume UTEP, Sourav Roy.
• Differential expression of stress-survival pathway genes related to Hispanic colorectal cancer disparities (2022), Volume New Orleans, Aditi Kulkarni, Urbashi Basnet, Abhijeet R. Patil, Rebecca DeJesus, Sourav Roy.
• Differential expression of stress-survival pathway genes related to Hispanic colorectal cancer disparities (2022), Volume Biological Sciences Research Building, UTEP, Sourav Roy.
• Stress-induced Differential miR-4633-5p Expression in Thyroid Cancer Health Disparities (2022), Jonathon Mancao, Sourav Roy, Salma Khan.
• Regulatory elements and gene regulatory networks: an insight into direct and indirect negative regulation by the ecdysone cascade in the Aedes aegypti (2021), Sourav Roy.
• Opportunities in Bioinformatics Research (2021), Sourav Roy.
• Bioinformatic Approaches for Identification of Gene Regulatory Elements and miRNA Targets (2021), Volume New Mexico State University, Sourav Roy.
• The gene expression profile of triple-negative breast cancer after neoadjuvant chemotherapy (2021), Sourav Roy, Alexander Philipovskiy.
• Bioinformatic Approaches for Identification of Gene Regulatory Elements and miRNA Targets (2020), Sourav Roy.
• Computational Biology and Covid 19 (2020), Sourav Roy.
• Gene regulatory elements and networks provide an insight into direct and indirect negative regulation by the ecdysone cascade (2019), Volume Sitges, Barcelona, Spain, Sourav Roy.
• Gene Regulatory Elements and Networks Provide an Insight into Direct and Indirect Negative Regulation by the Ecdysone cascade (2019), Volume Crete, Greece, Sourav Roy.

• R21: The role of tumor endothelium-specific prion-gene prnd in epithelial ovarian cancer
• Molecular and immune profiling of Hispanic gastrointestinal cancer disparities
• Identifying the components of oxidative stress-induced cellular survival pathways in colorectal cancer Hispanic health disparities
• FUTURE LEADERS – AFRICAN INDEPENDENT RESEARCH
• Oxidative stress induced cellular survival pathways in colorectal cancer health disparities
• R01:Molecular Basis of Ecdysteroid Action in the Mosquito